Used Mercedes-Benz S-Class for Sale near Indianapolis, IN
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2022 Mercedes-Benz S-Class
Shop 2022 Mercedes-Benz S-Class »With 774 currently listed for sale near Indianapolis, IN and an average price of $41,217.00, 25.2% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.66 / 5 stars.
78.4% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class is equipped with advanced technology, including a stunning 12.8-inch OLED touchscreen and a nine-speed automatic transmission with all-wheel drive.
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4.7 Overall rating
Customers say
The Mercedes-Benz S-Class has consistently impressed drivers with its luxurious feel, outstanding performance, and advanced technology across all model years. Owners particularly appreciate the comfortable and spacious interiors, the smooth ride, and the powerful engines. Many have praised features such as safety innovations and craftsmanship that highlight the brand's commitment to luxury. However, some common concerns among owners include high maintenance costs, issues with technology reliability, and a steep price tag compared to other models. Overall, the S-Class remains a top choice for those seeking a high-end driving experience.
AI generated from the text of customer reviews.
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What people say
Moises S
Reviewed a 2020 Mercedes-Benz S-Class on Jun 20, 2024
the features of an S class are the very reasons that this car is of good value. this is the flagship of Mercedes Benz so there is no comparison.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Mohit S
Reviewed a 2016 Mercedes-Benz S-Class on Apr 12, 2024
Awesome vehicle with luxury feels and style MB is best
Lee H
Reviewed a 2010 Mercedes-Benz S 550 on Jan 11, 2025
Everything is wonderful, except there is no audio bluetooth! Cell phone connects for calls, but not music. No other issues!
Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| S 500 4MATIC | $119,550 |
| S 580 4MATIC | $130,700 |
| Maybach S 680 4MATIC | $244,400 |
| AMG S 63 E Performance 4MATIC | $189,800 |
| S 580e 4MATIC | $130,400 |
| Maybach S 580 4MATIC | $207,150 |
Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of Mercedes-Benz S-Class prices has changed over time.
See more price trendsCarGurus recommends the 2022 Mercedes-Benz S-Class
Summary
With 774 currently listed for sale near Indianapolis, IN and an average price of $41,217.00, 25.2% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.66 / 5 stars.
78.4% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class is equipped with advanced technology, including a stunning 12.8-inch OLED touchscreen and a nine-speed automatic transmission with all-wheel drive.
Why it stands out
The 2022 Mercedes-Benz S-Class excels as the pinnacle of luxury sedans, offering an unparalleled blend of performance, comfort, and cutting-edge technology. Its refined design features a sleek profile and a meticulously crafted interior filled with premium materials. This model includes a state-of-the-art 12.8-inch OLED touchscreen, providing an intuitive interface for its MBUX infotainment system. With powerful engine options, including a turbocharged inline-six and twin-turbo V8, it delivers impressive performance without sacrificing fuel efficiency. The S-Class is also lauded for its robust safety features, ensuring a secure journey for all passengers. Overall, this model consistently impresses drivers seeking a high-end driving experience.
Other model years to consider
- Average price: $26,771.00
- Good/great deal percentage: 23.7%
- User rating: 4.88 / 5
- Total listings: 194
- Average price: $49,566.00
- Good/great deal percentage: 32.4%
- User rating: 4.76 / 5
- Total listings: 176
- Average price: $39,809.00
- Good/great deal percentage: 32.5%
- User rating: 4.85 / 5
- Total listings: 154
These recommendations are based on CarGurus' proprietary market data from March 31, 2026, CarGurus experts' opinions, and generative AI.
Recent expert test drives
2025 Mercedes-Benz S-Class
- Expert review7/10
- MSRP$117,750-$240,500
- Avg. price$152,961
- User rating0
2023 Mercedes-Benz S-Class
- Expert review9/10
- MSRP$114,500-$229,000
- Avg. price$82,589
- User rating4.2
2021 Mercedes-Benz S-Class
- Expert review8/10
- MSRP$109,800-$185,400
- Avg. price$66,591
- User rating5
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