Used 2021 Mercedes-Benz S-Class for Sale near Salem, OR
122 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 812 currently listed for sale and an average price of $61,878.00, 29.7% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
84.2% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a more sophisticated infotainment system, advanced safety features, and powerful engine options with hybrid technology.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 812 currently listed for sale and an average price of $61,878.00, 29.7% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
84.2% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a more sophisticated infotainment system, advanced safety features, and powerful engine options with hybrid technology.
Why it stands out
The 2021 Mercedes-Benz S-Class exemplifies luxury and performance in the full-size sedan category. Boasting advanced technology, the S-Class represents a significant update from its predecessor, featuring a sophisticated infotainment system that prioritizes driver convenience and comfort. Its two engine options—the 429-horsepower inline-six of the S500 and the robust 496-horsepower V8 of the S580—deliver impressive performance while incorporating hybrid technology for improved efficiency. The S-Class doesn't just cater to speed; it promises an extraordinarily comfortable ride with high-quality materials throughout its interior. Notable innovations like rear-wheel steering enhance its handling, while the luxurious cabin is designed around a minimalist aesthetic, featuring a large digital touchscreen and ambient lighting with 64 customizable options. While the price may be high, the combination of prestige, unparalleled features, and driving enjoyment makes the 2021 Mercedes-Benz S-Class a compelling choice for luxury car buyers.
Other model years to consider
- Average price: $66,420.00
- Good/great deal percentage: 28.3%
- User rating: 4.8 / 5
- Total listings: 1,122
- Average price: $25,670.00
- Good/great deal percentage: 32.4%
- User rating: 4.88 / 5
- Total listings: 953
- Average price: $21,752.00
- Good/great deal percentage: 32.8%
- User rating: 4.89 / 5
- Total listings: 789
This analysis is based on CarGurus' proprietary market data from April 6, 2026, CarGurus experts' opinions, and generative AI.
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Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
James B
Reviewed a 2021 Mercedes-Benz S 580 Sedan 4MATIC on Oct 14, 2024
The car is loaded with luxuries , very stylish at the same time sporty. You get a lot of car for the money and they hold there value. BMW would be close cusin to Mercedes.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
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