Used 2021 Mercedes-Benz S-Class for Sale near Philadelphia, PA
182 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 179 currently listed for sale near Philadelphia, PA and an average price of $59,632.00, 22.9% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
82.7% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features an upgraded infotainment system, enhanced powertrains, and boasts a luxurious interior redesigned with a minimalist approach.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 179 currently listed for sale near Philadelphia, PA and an average price of $59,632.00, 22.9% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
82.7% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features an upgraded infotainment system, enhanced powertrains, and boasts a luxurious interior redesigned with a minimalist approach.
Why it stands out
The 2021 Mercedes-Benz S-Class stands out as the flagship model of the luxury sedan segment, offering a combination of advanced technology and superior comfort that is hard to match. This iteration includes significant improvements such as an array of powertrains, including the robust V8 engine in the S580 4Matic, which delivers an impressive 496 horsepower. Owners appreciate the luxurious ride quality enhanced by standard air suspension and the innovative rear-wheel steering system that improves maneuverability.
The S-Class's interior is designed for maximum comfort, equipped with high-end materials and a highly customizable ambient lighting system that enhances the overall experience. The cutting-edge MBUX infotainment system adds to its appeal, providing a user-friendly interface complete with a 12.8-inch OLED touchscreen, wireless Apple CarPlay, and Android Auto. While the model maintains a high price point, enthusiasts agree that the S-Class sets a benchmark in performance and luxury that attracts those seeking the best in automotive engineering.
Other model years to consider
- Average price: $65,703.00
- Good/great deal percentage: 19.2%
- User rating: 4.8 / 5
- Total listings: 234
- Average price: $24,899.00
- Good/great deal percentage: 20.3%
- User rating: 4.88 / 5
- Total listings: 236
- Average price: $41,807.00
- Good/great deal percentage: 25.8%
- User rating: 4.76 / 5
- Total listings: 209
This analysis is based on CarGurus' proprietary market data from March 19, 2026, CarGurus experts' opinions, and generative AI.
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Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
James B
Reviewed a 2021 Mercedes-Benz S 580 Sedan 4MATIC on Oct 14, 2024
The car is loaded with luxuries , very stylish at the same time sporty. You get a lot of car for the money and they hold there value. BMW would be close cusin to Mercedes.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
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