Used 2021 Mercedes-Benz S-Class for Sale near Los Angeles, CA
192 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 192 currently listed for sale near Los Angeles, CA and an average price of $63,287.00, 32.8% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
83.9% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a revitalized infotainment system and offers two powerful engine configurations, providing an exceptional combination of luxury, advanced technology, and thrilling performance.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 192 currently listed for sale near Los Angeles, CA and an average price of $63,287.00, 32.8% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
83.9% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a revitalized infotainment system and offers two powerful engine configurations, providing an exceptional combination of luxury, advanced technology, and thrilling performance.
Why it stands out
The 2021 Mercedes-Benz S-Class is synonymous with luxury, embodying a perfect blend of sophisticated design and cutting-edge technology. It comes powered by impressive engine options, including a 3.0-liter turbocharged inline-six and a 4.0-liter twin-turbo V8, which deliver exhilarating performance—both models feature an advanced EQ Boost mild-hybrid system. The S-Class is celebrated not only for its athletic handling but also for its plush ride, bolstered by an air suspension system which enhances comfort. The reimagined interior is both minimalist and opulent, with spacious seating, exquisite materials, and an advanced infotainment setup that includes a large touchscreen and voice-control functionalities. With innovative features such as a rear-passenger airbag and a comprehensive suite of driver-assist technologies, the S-Class continues to set the bar for full-size luxury sedans.
Other model years to consider
- Average price: $69,507.00
- Good/great deal percentage: 32.3%
- User rating: 4.8 / 5
- Total listings: 269
- Average price: $28,476.00
- Good/great deal percentage: 17.8%
- User rating: 4.88 / 5
- Total listings: 197
- Average price: $102,128.00
- Good/great deal percentage: 30.9%
- User rating: 4.2 / 5
- Total listings: 282
This analysis is based on CarGurus' proprietary market data from April 7, 2026, CarGurus experts' opinions, and generative AI.
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Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
See more price trends
