Used Mercedes-Benz E-Class for Sale near Saint Louis, MO
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2022 Mercedes-Benz E-Class
Shop 2022 Mercedes-Benz E-Class »With 128 currently listed for sale near Saint Louis, MO and an average price of $41,420.00, 45.3% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
98.4% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class features an upscale interior with advanced technology and a luxurious driving experience, thanks to its turbocharged engines and robust performance.
FAQs
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4.6 Overall rating
Customers say
Overall, the Mercedes-Benz E-Class has built a strong reputation for luxury, comfort, and impressive performance across its various model years. Owners consistently praise features such as its powerful engines, smooth rides, and elegant interiors, indicating a preference for its refined driving experience and advanced technology. However, common criticisms include concerns about maintenance costs, the reliance on premium fuel, and the occasional feeling of underperformance in certain models. Despite these downsides, the E-Class remains a popular choice among drivers looking for a blend of quality and sophistication.
AI generated from the text of customer reviews.
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What people say
Ed L
Reviewed a 2012 Mercedes-Benz E-Class on Jul 25, 2024
It definitely has more than what Ive anticipated in terms of luxury, power, and comfort features....big difference compared to my BMW 528. Great value and I intend to keep it and enjoy driving it for a long time.
Michael R
Reviewed a 2018 Mercedes-Benz E-Class on Jun 1, 2024
I love the model...great size, comfortable interior, sporty, quick, all the bells and whistles.
Anonymous
Reviewed a 2022 Mercedes-Benz E-Class on Jul 12, 2024
Great value. 39K with 14K miles and in great condition with premium package. Took it to the Mercedes dealer for inspection and they said it was in great shape (tires, brakes, belts, filters, oil, fluid level, electronics, and even spark plugs). The interior was in pristine condition and the exterior is just as perfect.
Joseph V
Reviewed a 2018 Mercedes-Benz E-Class on Apr 14, 2024
This is truly a luxury convertible, Compare to BMW4 or Audi The E400 Cabriolet is not dependent on a Sport theme with a stiff ride, quick acceleration and hard cornering. Instead the Mercedes E Class is a true luxury, Touring vehicle that has more advanced technology and interior refinements than the BMW or Audi by far. The E 400 is Class a cut above, a car for those who demand the best. All 3 models are reliable and in the same price range, The Eclass has n=more rear leg room and is really the one true 4 seater for adults while the others have rear seats for children or packages. After weeks of research, reading numerous reviews and You Tube Reports, it was clear to us the 2018 E Class model year would give us the best vehicle and value for our dollar. Submitted By V8
Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| E 450 4MATIC | $72,300 |
| E 350 4MATIC | $66,400 |
| E 350 RWD | $63,900 |
| AMG E 53 Hybrid 4MATIC+ | $89,600 |
Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of Mercedes-Benz E-Class prices has changed over time.
See more price trendsCarGurus recommends the 2022 Mercedes-Benz E-Class

Summary
With 128 currently listed for sale near Saint Louis, MO and an average price of $41,420.00, 45.3% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
98.4% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class features an upscale interior with advanced technology and a luxurious driving experience, thanks to its turbocharged engines and robust performance.
Why it stands out
The 2022 Mercedes-Benz E-Class stands out in its segment for its impressive blend of luxury, performance, and technology. With offerings in various body styles, including coupe, convertible, and sedan, it caters to a wide range of preferences. The refreshed lineup boasts a modern design, advanced safety features, and a top-tier infotainment system that integrates seamlessly with user needs. Its turbocharged four-cylinder and six-cylinder engines deliver powerful performance, ensuring an exhilarating driving experience whether cruising on highways or navigating city streets. The high-quality materials used in the cabin provide a plush atmosphere, making every journey enjoyable.
Other model years to consider
- Average price: $29,130.00
- Good/great deal percentage: 31.4%
- User rating: 4.88 / 5
- Total listings: 175
- Average price: $22,232.00
- Good/great deal percentage: 27.2%
- User rating: 4.68 / 5
- Total listings: 202
- Average price: $46,513.00
- Good/great deal percentage: 50.5%
- User rating: 5 / 5
- Total listings: 97
These recommendations are based on CarGurus' proprietary market data from March 31, 2026, CarGurus experts' opinions, and generative AI.
Recent expert test drives

2024 Mercedes-Benz E-Class
- Expert review8/10
- MSRP$62,300-$68,100
- Avg. price$55,818
- User rating0

2020 Mercedes-Benz E-Class
- Expert review8/10
- MSRP$54,050-$111,750
- Avg. price$32,540
- User rating4.7778

2021 Mercedes-Benz E-Class
- Expert review8/10
- MSRP$54,250-$112,450
- Avg. price$38,702
- User rating4.5294
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