CarGurus Logo Homepage Link
  • Buy
    • Used cars
    • New cars
    • Certified pre-owned
    • Start your purchase online
    • Dealerships near me
  • Sell
    • Sell my car
    • Car values
    • Sell my car FAQs
  • Finance
    • Prequalify for financing
    • How does it work?
    • Financing FAQs
  • Research
    • Test drive reviews
    • Price trends
    • Tips & advice
    • Electric cars
    • Compare cars
  • Discover
    The latest way to shop:
    smarter research, better
    listings.
  • Saved cars & searches
  • Sign in / Register
    • My account
    • Saved searches
    • Saved cars
    • Recommended cars
    • Browsing history
    • Financing dashboard
      • United States (EN)
      • Estados Unidos (ES)
      • Canada (EN)
      • Canada (FR)
      • United Kingdom

Used 2022 Mercedes-Benz S-Class for Sale near Houston, TX

204 results
Houston, TX
2022 Mercedes-Benz S-Class S 580 4MATIC AWD Mercedes-Benz of Houston North

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

31,982 miles

$69,990

Fair Deal
Certified Pre-Owned
Houston, TX
18 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Gray (Selenite Grey)
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
31,982
Stock number:
NA108591
VIN:
W1K6G7GBXNA108591

Sponsored

2023 Mercedes-Benz S-Class S 580 4MATIC AWD

2023 Mercedes-Benz S-Class

S 580 4MATIC AWD

20,292 miles

$86,997

Fair Deal
Houston, TX
5 mi away
Year:
2023
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Manufaktur Diamond White
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Sienna Brown/Black
Transmission:
Automatic
Mileage:
20,292
Stock number:
PA224664
VIN:
W1K6G7GB6PA224664

Sponsored

2023 Mercedes-Benz S-Class S 580 4MATIC AWD

2023 Mercedes-Benz S-Class

S 580 4MATIC AWD

19,491 miles

$88,998

Fair Deal
Certified Pre-Owned
Conroe, TX
32 mi away
Year:
2023
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Selenite Gray Metallic
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Exclusive Sienna Brown/Black
Transmission:
9-Speed Automatic
Mileage:
19,491
Stock number:
U243216
VIN:
W1K6G7GB8PA243216

Sponsored

2021 Mercedes-Benz S-Class S 580 Sedan 4MATIC

2021 Mercedes-Benz S-Class

S 580 Sedan 4MATIC

31,665 miles

$61,782

Good Deal
Alvin, TX
23 mi away
Year:
2021
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
designo Diamond White
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Interior color:
Macchiato/Magma Gray
Transmission:
9-Speed Automatic
Mileage:
31,665
Stock number:
T29845
VIN:
W1K6G7GB5MA029845

2022 Mercedes-Benz S-Class S 580 4MATIC AWD

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

33,399 miles

$71,977

Fair Deal
Houston, TX
13 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Rubellite Re
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Transmission:
9-Speed Automatic
Mileage:
33,399
Stock number:
S260530A
VIN:
W1K6G7GB5NA106232

Preparing for a close up...

Photos coming soon

2021 Mercedes-Benz S-Class

S 580 Sedan 4MATIC

34,390 miles

$66,998

Fair Deal
Conroe, TX
32 mi away
Year:
2021
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
designo Diamond White Metallic
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Interior color:
Exclusive Sienna Brown/Black
Transmission:
9-Speed Automatic
Mileage:
34,390
Stock number:
U048303
VIN:
W1K6G7GB9MA048303

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

45,151 miles

$68,995

Fair Deal
Houston, TX
8 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Black
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Brown
Transmission:
9-Speed Automatic
Mileage:
45,151
Stock number:
104435-TCC
VIN:
W1K6G7GB9NA104435

Preparing for a close up...

Photos coming soon

2023 Mercedes-Benz S-Class

S 580 4MATIC AWD

20,292 miles

$86,997

Fair Deal
Houston, TX
5 mi away
Year:
2023
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Manufaktur Diamond White
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Sienna Brown/Black
Transmission:
Automatic
Mileage:
20,292
Stock number:
PA224664
VIN:
W1K6G7GB6PA224664

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

31,982 miles

$69,990

Fair Deal
Certified Pre-Owned
Houston, TX
18 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Gray (Selenite Grey)
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
31,982
Stock number:
NA108591
VIN:
W1K6G7GBXNA108591

Preparing for a close up...

Photos coming soon

2023 Mercedes-Benz S-Class

S 500 4MATIC AWD

50,737 miles

$61,797

Good Deal
Store transfer to Houston, TX
1,218 mi away • Price includes $1,799 shipping Price includes $1,799 shipping
Year:
2023
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
429 hp 3L I6
Exterior color:
Black
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Brown (TAN)
Transmission:
Automatic
Mileage:
50,737
Stock number:
28221009
VIN:
W1K6G6DB2PA180273

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

45,151 miles

$68,995

Fair Deal
Houston, TX
8 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Black
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Brown
Transmission:
9-Speed Automatic
Mileage:
45,151
Stock number:
104435-TCC
VIN:
W1K6G7GB9NA104435

Sponsored

  1. Home
  2. / Used Cars
  3. / Mercedes-Benz S-Class
  4. / 2022
  5. / Texas
  6. / Houston
Overview
Reviews
FAQs

CarGurus Analysis: 2022 Mercedes-Benz S-Class

Picture of 2022 Mercedes-Benz S-Class ## Summary - With 205 currently listed for sale near Houston, TX and an **average price of $67,144.00**, 16.1% of 2022 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2022 Mercedes-Benz S-Class 4.8 / 5 stars. - **88.8% of 2022 S-Class models on CarGurus are accident free**. - The 2022 Mercedes-Benz S-Class sedan is well-regarded for its luxury, featuring a state-of-the-art interior, advanced safety technologies, and powerful hybrid engine options. ## Why it stands out The 2022 Mercedes-Benz S-Class stands as a paragon of modern luxury in executive transportation. It boasts a grand presence, characterized by its sleek design, spacious cabin, and use of high-quality materials throughout. The model features a remarkable 48-volt mild hybrid powertrain that combines a turbocharged 3.0-liter inline-six engine in the S500 and a twin-turbo 4.0-liter V8 in the S580, offering all-wheel drive and exhilarating performance. In test drives, the S500 and S580 showed remarkable acceleration, clocking 0-60 mph times of 4.9 and 4.4 seconds, respectively, while providing a comfortable and smooth ride. Advanced technology, including the innovative OLED touchscreen display and an impressive driver assistance suite, elevates the driving experience, making this luxury sedan appealing to buyers seeking a blend of style, performance, and state-of-the-art features. ## Other model years to consider - **[2020 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2020-Mercedes-Benz-S-Class-Houston-c29725_L34369)** - Average price: $43,202.00 - Good/great deal percentage: 26.4% - User rating: 4.86 / 5 - Total listings: 140 - **[2018 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2018-Mercedes-Benz-S-Class-Houston-c27088_L34369)** - Average price: $32,778.00 - Good/great deal percentage: 21.4% - User rating: 4.76 / 5 - Total listings: 182 - **[2015 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2015-Mercedes-Benz-S-Class-Houston-c24430_L34369)** - Average price: $26,187.00 - Good/great deal percentage: 16.8% - User rating: 4.88 / 5 - Total listings: 197 This analysis is based on CarGurus' proprietary market data from March 24, 2026, CarGurus experts' opinions, and generative AI.

4.8 Overall rating

(15 reviews)
Anonymous
5.0
Reviewed a 2022 Mercedes-Benz S-Class on Jun 06, 2024

The only option I wish it had was the premier stereo system. Otherwise the car was perfect. It was basically a new vehicle. The price I actually paid was great based on the immaculate condition and very low mileage.

Joyce E
5.0
Reviewed a 2022 Mercedes-Benz S-Class on Apr 18, 2024

This car has a manufacturer recall on its fuel pump mechanism, and it is a hybrid car, so for someone who leaves the car parked in the garage for 2 straight weeks, it may cause the battery to die and may not be suited for my needs/lifestyle

Nabeel J
5.0
Reviewed a 2022 Mercedes-Benz S-Class on Apr 25, 2022

The S Class provides safety and comfort for its riders. At first, I decided to purchase the BMW 745e after comparing it with the Audi A8. I decided to give the Mercedes S class a try. After the test drive, I immediately decided to purchase the Mercedes S580. I do not regret my purchase at all. All of the looks of the car look fabulous. The ambient lighting is breathtaking as well as the display screen. The panoramic sunroof is also one of my favorites. I live in a hilly area, but I can’t even tell when going up the hill since the S580 is a powerful vehicle.

Sajid S
3.0
Reviewed a 2022 Mercedes-Benz S-Class on Dec 27, 2021

It’s been a pinnacle of luxury, however nothing stands out compared to previous models except some businesses including indoor lighting etc. the screen seems odd ;stands out in the middle and does not merge with the rest of the dashboard

Anonymous
5.0
Reviewed a 2022 Mercedes-Benz S-Class on Jan 27, 2025

Love the new car... The MB technology is amazing. The styling and comfort is some of the best in class

2022 Mercedes-Benz S-Class FAQs

How much does the 2022 Mercedes-Benz S-Class cost in Houston, TX?

The average 2022 Mercedes-Benz S-Class costs about $66,167.50. The average price has decreased by -6.5% since last year. The 204 for sale near Houston, TX on CarGurus, range from $48,104 to $445,529 in price.

Is the 2022 Mercedes-Benz S-Class a good car?

CarGurus experts gave the 2022 Mercedes-Benz S-Class an overall rating of 8.7/10 and 2022 Mercedes-Benz S-Class owners have rated the vehicle a 4.8/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Mercedes-Benz S-Class vehicles in Houston, TX have no reported accidents or damage?

184 out of 204 for sale near Houston, TX have no reported accidents or damage.

Is the 2022 Mercedes-Benz S-Class safe?

CarGurus experts gave the 2022 Mercedes-Benz S-Class a safety rating of 9/10.

What is the fuel economy of the 2022 Mercedes-Benz S-Class?

Depending on the engine and options, the 2022 Mercedes-Benz S-Class gets between 15 and 48 MPG (or EV battery range).

What fuel types are available?

Gasoline, Hybrid engines are available.

  • 2025 Mercedes-Benz S-Class in Houston TX

  • 2024 Mercedes-Benz S-Class in Houston TX

  • 2023 Mercedes-Benz S-Class in Houston TX

  • 2021 Mercedes-Benz S-Class in Houston TX

  • 2020 Mercedes-Benz S-Class in Houston TX

  • 2019 Mercedes-Benz S-Class in Houston TX

  • Mercedes-Benz S-Class S 580 4MATIC AWD

  • Mercedes-Benz S-Class S 500 4MATIC AWD

  • Mercedes-Benz S-Class Maybach S 680 4MATIC AWD

  • Mercedes-Benz S-Class Maybach S 580 4MATIC AWD in Houston TX

  • Jaguar XF in Houston TX

  • Audi A8 in Houston TX

  • BMW 7 Series in Houston TX

  • Mercedes-Benz S-Class in Houston TX

  • Used Mercedes-Benz Electric Cars for Sale

  • Popular Celebrity Cars for Sale in Houston TX

  • Affordable Luxury Cars For Sale in Houston TX

  • Used Luxury Cars for Sale in Houston TX

  • All Used Cars

  • Manual Transmission Cars

  • Luxury Cars

  • Cars with Red Interior

  • Cheap Manual Cars

  • Hybrid Cars

  • Sports Cars

  • Electric SUVs

  • Cheap Trucks

  • Small Cars

  • Third Row SUVs

  • Three Quarter Ton Trucks

  • Lifted Trucks

  • Manual Transmission Trucks

  • Diesel Trucks

  • Hybrid SUVs

  • Dually Trucks

  • One Ton Trucks

  • Cheap SUVs

  • Lifted Ford Trucks

  • 4x4 Trucks

  • Work Trucks

  • AWD SUVs

  • Ford Trucks

  • Chevrolet Trucks

  • Toyota Trucks

  • Trucks Under $10,000

  • Cars Under $15,000

  • Sports Cars Under $20,000

  • Trucks Under $20,000

  • Used Sedans for Sale with Low Mileage in Houston

  • Used SUVs / Crossovers for Sale with Low Mileage in Houston

  • Used Hatchbacks for Sale with Low Mileage in Houston

  • Used Convertibles for Sale with Low Mileage in Houston

  • Used Vans for Sale with Low Mileage in Houston

  • Used Minivans for Sale with Low Mileage in Houston

  • Used Pickup Trucks for Sale with Low Mileage in Houston

  • Used Coupes for Sale with Low Mileage in Houston

  • Used Wagons for Sale with Low Mileage in Houston

  • Mercedes-Benz of Houston Greenway

  • Mercedes-Benz of the Woodlands

  • Mercedes-Benz of Houston North

  • Star Motor Cars

  • Mercedes-Benz of Clear Lake

Connect with us
Download our app
Download on the App Store Get it on Google Play
  • Company
  • About CarGurus
  • Our team
  • Press
  • Investor relations
  • Price trends
  • Careers
  • Advertise with CarGurus
  • For dealers
  • Dealer signup
  • Dealer resources
  • Terms
  • Terms of use
  • Privacy policy
  • Interest-based ads
  • Security
  • Help
  • Help center
  • Contact us
Click for the BBB Business Review of this Auto Listing Service in Cambridge MA
    • United States (EN)
    • Estados Unidos (ES)
    • Canada (EN)
    • Canada (FR)
    • United Kingdom

© 2026 CarGurus, Inc., All Rights Reserved.