Used 2022 Mercedes-Benz E-Class for Sale near Fort Pierce, FL

## Summary - With 1,060 currently listed for sale and an **average price of $40,810.00**, 30.7% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars. - **83.9% of 2022 E-Class models on CarGurus are accident free**. - The 2022 Mercedes-Benz E-Class offers a turbocharged four-cylinder or six-cylinder power plant, standard automatic high-beam headlights, and impressive technology features like the MBUX infotainment system. ## Why it stands out The 2022 Mercedes-Benz E-Class sets itself apart in the luxury vehicle segment with a combination of elegance, performance, and advanced technology. Following a significant refresh in 2021, this model showcases refined styling with options for a coupe, convertible, sedan, or station wagon body style, catering to diverse preferences. Notably, the E-Class includes the MBUX infotainment system, featuring two high-resolution screens that enhance driver interaction while maintaining simplicity of use. The cabin offers an unrivaled luxury experience, complete with optional features such as heated and ventilated seats, and high-end sound systems. Performance-wise, the E-Class impresses with the turbocharged 3.0-liter inline-six engine available in the AMG E53 variant, producing 429 horsepower and accelerating from 0 to 60 mph in just 4.4 seconds. The vehicle also includes active safety features like automated emergency braking and blind-spot monitoring, ensuring peace of mind on the road. While some may find the base models less engaging, customizing the E-Class to suit individual tastes adds to its allure, making it a strong contender for luxury car buyers seeking both performance and sophistication. ## Other model years to consider - **[2015 Mercedes-Benz E-Class](https://www.cargurus.com/Cars/l-Used-2015-Mercedes-Benz-E-Class-c24582)** - Average price: $14,822.00 - Good/great deal percentage: 34.4% - User rating: 4.64 / 5 - Total listings: 1,375 - **[2019 Mercedes-Benz E-Class](https://www.cargurus.com/Cars/l-Used-2019-Mercedes-Benz-E-Class-c28109)** - Average price: $27,896.00 - Good/great deal percentage: 31.3% - User rating: 4.88 / 5 - Total listings: 1,107 - **[2017 Mercedes-Benz E-Class](https://www.cargurus.com/Cars/l-Used-2017-Mercedes-Benz-E-Class-c25753)** - Average price: $18,528.00 - Good/great deal percentage: 32.1% - User rating: 4.6 / 5 - Total listings: 1,322 This analysis is based on CarGurus' proprietary market data from March 23, 2026, CarGurus experts' opinions, and generative AI.