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Used 2021 Mercedes-Benz S-Class for Sale near Naples, FL

159 results
Naples, FL
2020 Mercedes-Benz S-Class S 560 Sedan RWD Taverna INFINITI North Miami

2020 Mercedes-Benz S-Class

S 560 Sedan RWD

61,166 miles

$35,698

Great Deal
West Park, FL
99 mi away
Year:
2020
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
463 hp 4L V8
Exterior color:
White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
White
Transmission:
9-Speed Automatic
Mileage:
61,166
Stock number:
NV502088
VIN:
WDDUG8DB1LA502088

Sponsored

2020 Mercedes-Benz S-Class S 450 4MATIC Sedan AWD

2020 Mercedes-Benz S-Class

S 450 4MATIC Sedan AWD

77,908 miles

$29,997

Good Deal
Coconut Creek, FL
99 mi away
Year:
2020
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
3L V6
Exterior color:
Diamond Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Oyster
Transmission:
9-Speed Automatic
Mileage:
77,908
Stock number:
CS501841
VIN:
WDDUG6EB9LA501841

Sponsored

2022 Mercedes-Benz S-Class S 580 4MATIC AWD

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

24,140 miles

$73,389

Fair Deal
Certified Pre-Owned
Sarasota, FL
88 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Black
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Sienna Brown/Black
Transmission:
Automatic
Mileage:
24,140
Stock number:
NA111959
VIN:
W1K6G7GB1NA111959

Sponsored

2022 Mercedes-Benz S-Class S 580 4MATIC AWD

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

28,723 miles

$65,999

Good Deal
Fort Lauderdale, FL
99 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Obsidian Black/designo Diamond White
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
9-Speed Automatic
Mileage:
28,723
Stock number:
PNA086176
VIN:
W1K6G7GB7NA086176

2020 Mercedes-Benz S-Class S 560 Sedan RWD

2020 Mercedes-Benz S-Class

S 560 Sedan RWD

46,563 miles

$43,495

Fair Deal
Coconut Creek, FL
99 mi away
Year:
2020
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
463 hp 4L V8
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black Nappa
Transmission:
9-Speed Automatic
Mileage:
46,563
Stock number:
M569338
VIN:
W1KUG8DB3LA569338

2022 Mercedes-Benz S-Class S 580 4MATIC AWD

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

28,866 miles

$72,508

Fair Deal
Cutler Bay, FL
97 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
MANUFAKTUR Diamond White
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Exclusive Carmine Red/Black
Transmission:
9-Speed Automatic
Mileage:
28,866
Stock number:
P120657
VIN:
W1K6G7GB8NA120657

Preparing for a close up...

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2020 Mercedes-Benz S-Class

S 560 4MATIC Sedan AWD

66,368 miles

$36,429

Good Deal
West Park, FL
99 mi away
Year:
2020
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
463 hp 4L V8
Exterior color:
Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Brown
Transmission:
9-Speed Automatic
Mileage:
66,368
Stock number:
NV559215
VIN:
W1KUG8GB9LA559215

Preparing for a close up...

Photos coming soon

2021 Mercedes-Benz S-Class

S 580 Sedan 4MATIC

75,740 miles

$46,999

Good Deal
Miramar, FL
99 mi away
Year:
2021
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Transmission:
9-Speed Automatic
Mileage:
75,740
Stock number:
047356
VIN:
W1K6G7GB3MA047356

Preparing for a close up...

Photos coming soon

2020 Mercedes-Benz S-Class

S 560 Sedan RWD

61,166 miles

$35,698

Great Deal
West Park, FL
99 mi away
Year:
2020
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
463 hp 4L V8
Exterior color:
White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
White
Transmission:
9-Speed Automatic
Mileage:
61,166
Stock number:
NV502088
VIN:
WDDUG8DB1LA502088

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

32,992 miles

$70,611

Fair Deal
Doral, FL
94 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
MANUFAKTUR Diamond White
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Macchiato/Magma Gray
Transmission:
Automatic
Mileage:
32,992
Stock number:
M912848
VIN:
W1K6G7GB2NA087767

Preparing for a close up...

Photos coming soon

2020 Mercedes-Benz S-Class

S 450 4MATIC Sedan AWD

77,908 miles

$29,997

Good Deal
Coconut Creek, FL
99 mi away
Year:
2020
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
3L V6
Exterior color:
Diamond Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Oyster
Transmission:
9-Speed Automatic
Mileage:
77,908
Stock number:
CS501841
VIN:
WDDUG6EB9LA501841

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 500 4MATIC AWD

20,114 miles

$68,449

Fair Deal
Certified Pre-Owned
Cutler Bay, FL
97 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
429 hp 3L I6
Exterior color:
Graphite Gray Metallic
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
9-Speed Automatic
Mileage:
20,114
Stock number:
P122920
VIN:
W1K6G6DB9NA122920

Preparing for a close up...

Photos coming soon

2021 Mercedes-Benz S-Class

S 500 Sedan 4MATIC

26,373 miles

$59,998

Fair Deal
Sarasota, FL
88 mi away
Year:
2021
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
429 hp 3L I6
Exterior color:
Silver
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
26,373
Stock number:
46172B
VIN:
W1K6G6DB5MA032680

Preparing for a close up...

Photos coming soon

2020 Mercedes-Benz S-Class

S 560 Sedan RWD

40,319 miles

$44,947

Fair Deal
Cape Coral, FL
38 mi away
Year:
2020
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
463 hp 4L V8
Exterior color:
designo Cashmere White Magno
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Porcelain/Black
Transmission:
9-Speed Automatic
Mileage:
40,319
Stock number:
WP12609
VIN:
WDDUG8DBXLA524252

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

24,140 miles

$73,389

Fair Deal
Certified Pre-Owned
Sarasota, FL
88 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Black
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Interior color:
Sienna Brown/Black
Transmission:
Automatic
Mileage:
24,140
Stock number:
NA111959
VIN:
W1K6G7GB1NA111959

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 500 4MATIC AWD

41,211 miles

$55,985

Good Deal
Miami, FL
97 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
429 hp 3L I6
Exterior color:
Silver
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
41,211
Stock number:
A087988
VIN:
W1K6G6DB9NA087988

Preparing for a close up...

Photos coming soon

2021 Mercedes-Benz S-Class

S 580 Sedan 4MATIC

39,450 miles

$60,795

Fair Deal
Margate, FL
99 mi away
Year:
2021
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Designo Diamond White
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Interior color:
Gray (Macchiato/Magma Grey)
Transmission:
Automatic
Mileage:
39,450
Stock number:
MA033301
VIN:
W1K6G7GB7MA033301

Preparing for a close up...

Photos coming soon

2022 Mercedes-Benz S-Class

S 580 4MATIC AWD

25,994 miles

$71,000

Fair Deal
Miami, FL
96 mi away
Year:
2022
Make:
Mercedes-Benz
Model:
S-Class
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
496 hp 4L V8
Exterior color:
Nautical Blue Metallic
Combined gas mileage:
20 MPG
Fuel type:
Gasoline
Transmission:
9-Speed Automatic
Mileage:
25,994
Stock number:
NA145382
VIN:
W1K6G7GBXNA145382

Sponsored

  1. Home
  2. / Used Cars
  3. / Mercedes-Benz S-Class
  4. / 2021
  5. / Florida
  6. / Naples
Overview
Reviews
FAQs

CarGurus Analysis: 2021 Mercedes-Benz S-Class

Picture of 2021 Mercedes-Benz S-Class ## Summary - With 804 currently listed for sale and an **average price of $61,412.00**, 32.3% of 2021 Mercedes-Benz S-Class vehicles for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars. - **85.3% of 2021 S-Class models on CarGurus are accident free**. - The 2021 Mercedes-Benz S-Class features a redesigned infotainment system, powerful engine options, and advanced driver-assist technologies, along with a luxurious interior that enhances comfort and tech integration. ## Why it stands out The 2021 Mercedes-Benz S-Class excels in the luxury sedan market, combining powerful engine options with cutting-edge technology and unparalleled comfort. Available in two configurations, the S500 4Matic and S580 4Matic, it features advanced powertrains, including a 3.0-liter inline-six and a 4.0-liter twin-turbo V8 that deliver impressive performance. The interior is a blend of sophistication and tech, highlighted by a minimalist design that includes a massive OLED touchscreen and extensive ambient lighting. Although some users have noted issues with the run-flat tires, the overall feedback reflects a very positive reception, making it a desirable choice for those seeking luxury and innovation. ## Other model years to consider - **[2022 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2022-Mercedes-Benz-S-Class-c31858)** - Average price: $66,168.00 - Good/great deal percentage: 31.4% - User rating: 4.8 / 5 - Total listings: 1,089 - **[2015 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2015-Mercedes-Benz-S-Class-c24430)** - Average price: $25,643.00 - Good/great deal percentage: 31.5% - User rating: 4.88 / 5 - Total listings: 956 - **[2014 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2014-Mercedes-Benz-S-Class-c24217)** - Average price: $21,743.00 - Good/great deal percentage: 31.1% - User rating: 4.89 / 5 - Total listings: 792 This analysis is based on CarGurus' proprietary market data from March 30, 2026, CarGurus experts' opinions, and generative AI.

5 Overall rating

(7 reviews)
Chris V
5.0
Reviewed a 2021 Mercedes-Benz S-Class on Jun 05, 2024

This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.

Deno P
5.0
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023

This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.

Rob G
5.0
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022

Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.

James B
5.0
Reviewed a 2021 Mercedes-Benz S 580 Sedan 4MATIC on Oct 14, 2024

The car is loaded with luxuries , very stylish at the same time sporty. You get a lot of car for the money and they hold there value. BMW would be close cusin to Mercedes.

Bob D
5.0
Reviewed a 2021 Mercedes-Benz S-Class on Mar 15, 2024

Gently used, beautifully maintained, a real classic. Price was a little too much, otherwise I would have signed the deal.

2021 Mercedes-Benz S-Class FAQs

How much does the 2021 Mercedes-Benz S-Class cost in Naples, FL?

The average 2021 Mercedes-Benz S-Class costs about $61,412.33. The average price has decreased by -5.6% since last year. The 156 for sale near Naples, FL on CarGurus, range from $27,382 to $181,618 in price.

Is the 2021 Mercedes-Benz S-Class a good car?

CarGurus experts gave the 2021 Mercedes-Benz S-Class an overall rating of 7.5/10 and 2021 Mercedes-Benz S-Class owners have rated the vehicle a 5/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2021 Mercedes-Benz S-Class vehicles in Naples, FL have no reported accidents or damage?

122 out of 156 for sale near Naples, FL have no reported accidents or damage.

Is the 2021 Mercedes-Benz S-Class safe?

CarGurus experts gave the 2021 Mercedes-Benz S-Class a safety rating of 7/10.

What is the fuel economy of the 2021 Mercedes-Benz S-Class?

Depending on the engine and options, the 2021 Mercedes-Benz S-Class gets between 16 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

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