Used 2021 Mercedes-Benz E-Class for Sale near Philadelphia, PA

## Summary - With 178 currently listed for sale near Philadelphia, PA and an **average price of $49,975.00**, 29.8% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2021 Mercedes-Benz E-Class 4.53 / 5 stars. - **86.0% of 2021 E-Class models on CarGurus are accident free**. - The 2021 Mercedes-Benz E-Class features a refined design with updated tech, multiple powertrain options, and a luxurious interior filled with high-quality materials. ## Why it stands out The 2021 Mercedes-Benz E-Class remains a standout in the midsize luxury car segment due to its exceptional blend of performance, luxury, and advanced technology. Offering four body styles and numerous powertrain options—including a hybrid inline-six engine—the E-Class has something for every kind of buyer. This mid-cycle refresh enhances its infotainment system and exterior styling, making it even more appealing. Owners appreciate its fast speed, comfortable handling, and stunning design, though some have noted concerns about features such as lane keeping assist and the use of artificial leather. The cabin is a luxurious retreat, rich in materials and equipped with modern technological advancements like the MBUX infotainment system, which adds to the driving experience. Despite its lofty price tag, this car continues to meet and exceed expectations for those willing to invest in luxury. ## Other model years to consider - **[2022 Mercedes-Benz E-Class](https://www.cargurus.com/Cars/l-Used-2022-Mercedes-Benz-E-Class-Philadelphia-c31854_L30895)** - Average price: $39,252.00 - Good/great deal percentage: 29.2% - User rating: 5 / 5 - Total listings: 192 - **[2019 Mercedes-Benz E-Class](https://www.cargurus.com/Cars/l-Used-2019-Mercedes-Benz-E-Class-Philadelphia-c28109_L30895)** - Average price: $32,527.00 - Good/great deal percentage: 27.1% - User rating: 4.88 / 5 - Total listings: 247 - **[2018 Mercedes-Benz E-Class](https://www.cargurus.com/Cars/l-Used-2018-Mercedes-Benz-E-Class-Philadelphia-c27070_L30895)** - Average price: $22,779.00 - Good/great deal percentage: 26.7% - User rating: 4.68 / 5 - Total listings: 277 This analysis is based on CarGurus' proprietary market data from March 24, 2026, CarGurus experts' opinions, and generative AI.