Used 2021 Mercedes-Benz E-Class for Sale near Newark, DE

## Summary - With 885 currently listed for sale and an **average price of $38,714.00**, 28.0% of 2021 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2021 Mercedes-Benz E-Class 4.53 / 5 stars. - **75.8% of 2021 E-Class models on CarGurus are accident-free**. - The 2021 Mercedes-Benz E-Class features a mid-cycle update to the infotainment system, a new electrified inline-six engine option, and continued luxury and performance that the E-Class is known for. ## Why it stands out The 2021 Mercedes-Benz E-Class continues to impress with its blend of performance, luxury, and advanced technology. With multiple powertrain options, including the new hybrid system in the E450 variant, drivers can choose a model that fits their desired balance of power and efficiency. The E-Class offers a smooth and comfortable ride, enhanced by a high-quality interior featuring rich materials and user-friendly technology. Notably, the updated MBUX infotainment system now allows for touch interactions, improving usability over previous iterations. While the car is remarkably well-regarded, some buyers may find the advanced safety features to be only optional, which could be a consideration while shopping. Overall, the 2021 E-Class stands out as a sophisticated and versatile luxury vehicle, appealing to those who seek both style and substance. ## Other model years to consider - **[2015 Mercedes-Benz E-Class](https://www.cargurus.com/Cars/l-Used-2015-Mercedes-Benz-E-Class-c24582)** - Average price: $14,946.00 - Good/great deal percentage: 36.4% - User rating: 4.64 / 5 - Total listings: 1,358 - **[2022 Mercedes-Benz E-Class](https://www.cargurus.com/Cars/l-Used-2022-Mercedes-Benz-E-Class-c31854)** - Average price: $41,109.00 - Good/great deal percentage: 28.6% - User rating: 5 / 5 - Total listings: 1,064 - **[2019 Mercedes-Benz E-Class](https://www.cargurus.com/Cars/l-Used-2019-Mercedes-Benz-E-Class-c28109)** - Average price: $27,916.00 - Good/great deal percentage: 31.5% - User rating: 4.88 / 5 - Total listings: 1,125 This analysis is based on CarGurus' proprietary market data from March 30, 2026, CarGurus experts' opinions, and generative AI.