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Used 2021 Lexus RX for Sale near Fort Myers, FL

122 results
Fort Myers, FL
2022 Lexus RX 350 FWD Lexus of Sarasota

2022 Lexus RX

350 FWD

21,876 miles

$41,364

Good Deal
Certified Pre-Owned
Sarasota, FL
59 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
21,876
Stock number:
C073509A
VIN:
2T2HZMAA4NC250020

Sponsored

2021 Lexus RX 350L FWD

2021 Lexus RX

350L FWD

61,748 miles

$34,681

Good Deal
Sarasota, FL
59 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
61,748
Stock number:
A356707A
VIN:
JTJHZKEAXM2018602

Sponsored

2022 Lexus RX 350 FWD

2022 Lexus RX

350 FWD

58,424 miles

$33,983

Good Deal
Sarasota, FL
58 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Mileage:
58,424
Stock number:
9338162A
VIN:
2T2AZMAA2NC221116

Sponsored

2022 Lexus RX 350 FWD

2022 Lexus RX

350 FWD

33,039 miles

$39,110

Good Deal
Naples, FL
23 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
33,039
Stock number:
598367A
VIN:
2T2HZMAA7NC244549

2022 Lexus RX 350 FWD

2022 Lexus RX

350 FWD

33,786 miles

$35,003

Great Deal
Venice, FL
48 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
33,786
Stock number:
NC237833
VIN:
2T2AZMAA0NC237833

2021 Lexus RX 350 AWD

2021 Lexus RX

350 AWD

71,825 miles

$29,441

Great Deal
Sarasota, FL
59 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
71,825
Stock number:
5075165A
VIN:
2T2HZMDA2MC277954

Preparing for a close up...

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2020 Lexus RX

350 FWD

106,089 miles

$24,778

Good Deal
Sarasota, FL
59 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
106,089
Stock number:
C119923A
VIN:
2T2HZMAA2LC181437

Preparing for a close up...

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2022 Lexus RX

350 FWD

50,632 miles

$32,998

Great Deal
Naples, FL
33 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
50,632
Stock number:
28228760
VIN:
2T2AZMAAXNC225267

Preparing for a close up...

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2021 Lexus RX

350 AWD

75,456 miles

$29,777

Great Deal
Sarasota, FL
59 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
75,456
Stock number:
C123252A
VIN:
2T2HZMDA2MC275802

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350L FWD

61,748 miles

$34,681

Good Deal
Sarasota, FL
59 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
61,748
Stock number:
A356707A
VIN:
JTJHZKEAXM2018602

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

33,916 miles

$35,916

Good Deal
Naples, FL
29 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
33,916
Stock number:
I224698
VIN:
2T2AZMAAXNC224698

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

36,700 miles

$40,897

Fair Deal
Store transfer to Fort Myers, FL
749 mi away • Price includes $899 shipping Price includes $899 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White
Transmission:
Automatic
Mileage:
36,700
Stock number:
28160000
VIN:
2T2HZMAA8NC256984

Preparing for a close up...

Photos coming soon

2020 Lexus RX

350 FWD

38,830 miles

$38,247

Fair Deal
Store transfer to Fort Myers, FL
472 mi away • Price includes $249 shipping Price includes $249 shipping
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Red (Burgundy)
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
CREAM
Transmission:
Automatic
Mileage:
38,830
Stock number:
27799110
VIN:
2T2HZMAA7LC178176

Preparing for a close up...

Photos coming soon

2020 Lexus RX

350 FWD

36,998 miles

$36,447

Good Deal
Store transfer to Fort Myers, FL
562 mi away • Price includes $449 shipping Price includes $449 shipping
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
Automatic
Mileage:
36,998
Stock number:
28432433
VIN:
2T2HZMAA1LC174513

Preparing for a close up...

Photos coming soon

2020 Lexus RX

350 FWD

59,853 miles

$32,997

Fair Deal
Store transfer to Fort Myers, FL
2,322 mi away • Price includes $1,999 shipping Price includes $1,999 shipping
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
Automatic
Mileage:
59,853
Stock number:
28247458
VIN:
2T2HZMAA5LC167371

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 F Sport Handling AWD

28,712 miles

$40,985

Great Deal
Certified Pre-Owned
Port Charlotte, FL
29 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Matador Red Mica
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
28,712
Stock number:
T723A
VIN:
2T2YZMDA7NC331900

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

40,732 miles

$37,951

Fair Deal
Fort Myers, FL
7 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
40,732
Stock number:
B062413A
VIN:
2T2HZMAA8NC248075

Preparing for a close up...

Photos coming soon

2020 Lexus RX

350L AWD

84,254 miles

$30,921

Good Deal
Naples, FL
24 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Transmission:
8-Speed Automatic
Mileage:
84,254
Stock number:
TJ026871A
VIN:
JTJHZKFA8L2022838

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

35,638 miles

$39,999

Fair Deal
Certified Pre-Owned
Sarasota, FL
59 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
35,638
Stock number:
C136671A
VIN:
2T2HZMAA9NC259604

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 F Sport Handling AWD

45,743 miles

$40,999

Fair Deal
Lake Wales, FL
87 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
45,743
Stock number:
5P2062A
VIN:
2T2YZMDA4NC353515

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2021
  5. / Florida
  6. / Fort Myers
Overview
Reviews
FAQs

CarGurus Analysis: 2021 Lexus RX

Picture of 2021 Lexus RX ## Summary - With 1,256 currently listed for sale and an **average price of $35,671.00**, 33.1% of 2021 Lexus RX models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2021 Lexus RX 4.73 / 5 stars. - **75.6% of 2021 RX models on CarGurus are accident-free**. - The 2021 Lexus RX offers a comfortable ride with a potent 3.5-liter V6 engine, accommodating seating, and a range of luxury features. Notably, it includes new standard safety systems for enhanced protection. ## Why it stands out The 2021 Lexus RX stands out as a luxurious midsize SUV that combines reliability with comfort and performance. It features a smooth 3.5-liter V6 engine delivering 295 horsepower, paired with an eight-speed automatic transmission that ensures a refined driving experience. The RX is lauded for its plush interiors and advanced safety features, emphasizing Lexus' commitment to quality and reliability. Significant upgrades for 2021 include enhanced standard safety technology through the Lexus Safety System+ 2.0, which offers a suite of driver-assistance features. Although some owners desire more cargo space and have pointed out that the braking performance could be improved, the RX is popular among buyers seeking a dependable and luxurious driving experience. From its pleasing design to its extensive comfort options, the 2021 RX continues to affirm its status as one of America’s favorite luxury SUVs. ## Other model years to consider - **[2020 Lexus RX](https://www.cargurus.com/Cars/l-Used-2020-Lexus-RX-c29337)** - Average price: $33,152.00 - Good/great deal percentage: 34.7% - User rating: 4.77 / 5 - Total listings: 1,092 - **[2022 Lexus RX](https://www.cargurus.com/Cars/l-Used-2022-Lexus-RX-c31847)** - Average price: $39,940.00 - Good/great deal percentage: 32.6% - User rating: 4.58 / 5 - Total listings: 2,001 - **[2023 Lexus RX](https://www.cargurus.com/Cars/l-Used-2023-Lexus-RX-c32334)** - Average price: $47,134.00 - Good/great deal percentage: 31.9% - User rating: 4.62 / 5 - Total listings: 2,444 This analysis is based on CarGurus' proprietary market data from March 23, 2026, CarGurus experts' opinions, and generative AI.

4.8 Overall rating

(26 reviews)
Archie C
5.0
Reviewed a 2021 Lexus RX on Oct 13, 2024

Very reliable stylish looking drives well. Good suspension. Fun to drive

Haidar A
5.0
Reviewed a 2021 Lexus 350L AWD on Apr 25, 2024

The car is perfect if only the brakes were as responsive of a German car.

Ann W
5.0
Reviewed a 2021 Lexus RX on Feb 22, 2023

This car is beautiful and drives so smooth.

Anonymous
5.0
Reviewed a 2021 Lexus RX on Nov 04, 2023

Perfect for me and my family (except for the Parchment interior that my kids will probably ruin) but I love it!so I will do everything to keep it clean.. this car is superior family luxury! Have kid? Needs spacious trunk and seating but doesnt want it looking huge and bulky outside? Needs reliability? Need quality? Need LUXURY? look no further the RX 350 IS THE CAR FOR YOU!

Dan F
5.0
Reviewed a 2021 Lexus RX on Mar 26, 2024

Condition of the vehicle was 10/10. Interior was detailed extremely well. Mechanically it all checked out as well. Only issue was since it is a Canadian vehicle the digital climate controls appear to be stuck in Celsius. Could be a troubleshoot to resolve it but other than that perfect vehicle.

2021 Lexus RX FAQs

How much does the 2021 Lexus RX cost in Fort Myers, FL?

The average 2021 Lexus RX costs about $35,762.39. The average price has decreased by -2.1% since last year. The 101 for sale near Fort Myers, FL on CarGurus, range from $25,827 to $52,608 in price.

Is the 2021 Lexus RX a good car?

CarGurus experts gave the 2021 Lexus RX an overall rating of 7.8/10 and 2021 Lexus RX owners have rated the vehicle a 4.7/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2021 Lexus RX vehicles in Fort Myers, FL have no reported accidents or damage?

101 out of 101 for sale near Fort Myers, FL have no reported accidents or damage.

Is the 2021 Lexus RX safe?

CarGurus experts gave the 2021 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2021 Lexus RX?

Depending on the engine and options, the 2021 Lexus RX gets between 21 and 23 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

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